Tetanus in Injecting Drug Users, United Kingdom
نویسندگان
چکیده
6. Li T, Qiu Z, Zhang L, Han Y, He W, Liu Z, et al. Significant changes of peripheral T lymphocyte subsets in patients with severe acute respiratory syndrome. J Infect Dis. 2004;189:648–51. 7. Griffin DE, Bellini WJ. Measles. In: Fields BN, editor. Virology. New York: Raven Press; 1996. p. 1267–312. 8. Havlir DV, Barnes PF. Current concepts: tuberculosis in patients with human immunodeficiency virus infection. N Engl J Med. 1999;340:367–73. 9. Frieden TR, Sterling TR, Munsiff SS, Watt CJ, Dye C. Tuberculosis. Lancet. 2003;362:887–99.
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Improvement in laboratory diagnosis of wound botulism and tetanus among injecting illicit-drug users by use of real-time PCR assays for neurotoxin gene fragments.
An upsurge in wound infections due to Clostridium botulinum and Clostridium tetani among users of illegal injected drugs (IDUs) occurred in the United Kingdom during 2003 and 2004. A real-time PCR assay was developed to detect a fragment of the neurotoxin gene of C. tetani (TeNT) and was used in conjunction with previously described assays for C. botulinum neurotoxin types A, B, and E (BoNTA, -...
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